Polycystic kidney disease patients to make the most painful is that back pain, painkillers and therefore became a necessity of life, but not abuse painkillers, because many painkillers have side effects, and even a lot of damage to the kidneys is also great, so to proper use of appropriate painkillers, but do not rely on any kind of long-term painkillers. Analgesics can be divided into three categories, 1. Antipyretic analgesic anti-inflammatory drugs. 2. The central painkillers. 3. narcotic analgesics, patients with polycystic kidney fragile, not all painkillers can be used. Improper use will cause unnecessary damage or addicted to drug addiction.
1. antipyretic analgesic anti-inflammatory drugs
Aspirin
Aspirin is a long history of painkillers, long-term use of aspirin may occur interstitial nephritis, renal papillary necrosis, renal dysfunction. Such large doses of painkillers can lead to oxidative phosphorylation coupled to resolve, potassium escape from renal tubular cells, resulting in potassium, uric acid excretion in the urine is too high, a larger damage can occur in the lower urinary proteins, cells, casts Wait. In fact, part of the renal pelvis cancer is likely to be abused aspirin secondary complications, increase the risk of kidney failure, renal toxicity, and therefore do not recommend long-term use.
Indomethacin
It can cause high blood pressure, vasculitis, edema.
There may be hematuria. Elderly patients may be a transient renal insufficiency.
And triamterene combination can cause kidney damage
Disable ulcer disease, tremor paralysis, mental illness, epilepsy, bronchial asthma, liver and kidney dysfunction, pregnant and lactating women.
Someone with indomethacin treatment of chronic glomerulonephritis, the result is increased urinary protein, facial swelling increased, stopping a few days after the symptoms improve. Newborns receiving high doses of indomethacin treatment may cause mild renal dysfunction, manifested as decreased urine output, increased serum creatinine temporary, so renal dysfunction should be used with caution.
Indomethacin and aspirin should not be combined:
Because aspirin can make indomethacin decreased absorption in the gastrointestinal tract, reducing the blood concentration, weakened, while at the same stimulation to enhance its digestive tract may cause bleeding, so the combination of the two drugs should be avoided or used with caution. Gastric ulcer patients should strictly prohibited combination.
Indomethacin and phenylbutazone or prednisone should not be combined:
Because the non-steroidal anti-inflammatory pain analgesic, proved that it can enhance Bute and glucocorticoid-induced ulcer effect, it generally should not be used in combination.
Phenylbutazone
Bute potentially toxic to the kidneys, can cause acute renal failure, renal papillary necrosis and interstitial nephritis. Occurred mainly in patients taking aspirin or other anti-inflammatory drugs, in addition proteinuria may also occur, pyelonephritis and cystitis. Animal experiments show that it can cause reduced renal blood flow and glomerular filtration rate and reduce prostaglandin E synthesis.
Paracetamol
Toxic metabolites generated by excess acetaminophen can damage the kidneys also cause kidney cell necrosis, especially when combined with sodium salicylate or caffeine, more damage to the kidneys.
White with black, the new Contac, day and night one hundred Ning, a sense of health, crack, Tylenol, Ganmaoling, Parco inclusive of paracetamol and other common cold medicines, these drugs should not eat at the same time. In addition, aspirin, painkillers, paracetamol and gentamicin, kanamycin, also have kidney toxicity.
2. The central analgesics
Tramadol
Excessive use can cause memory loss, unresponsive; loss of appetite, weight loss; constipation, urinary retention; decreased sexual function. In addition, the "seizure" is a very important complication after tramadol addiction, so for young people without a family history of epilepsy seizures, parents must first rule whether the child abuse tramadol. After tramadol addiction can also lead to psychological abnormalities and personality changes, such as lying, scam, grumpy, reluctant to communicate with others, self-esteem, self-closing, self-abuse, suicide and other serious damage to family relationships and social functions, tramadol into After the addiction is not treated or not treated properly, is easy on the road to drugs or robbery and other crimes.
3. narcotic analgesics
Such drugs have addictive properties, but also countries such substances strict supervision, can not just use, if addiction, will be more difficult. Representative drugs such drugs as morphine, pethidine and the like.
Therefore, there is a risk painkillers, medication need to be cautious. More painkillers belong to Western medicine, the human body great harm, our hospital of traditional Chinese medicine research and development of micro-osmotic treatment of conservative therapy by many patients with high praise, welcome patients to the clinics, if in doubt ask questions to our online experts, or leave a message on the message board, also can send e-mail to expert advice kidneyfailuretreat@hotmail.com.
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