Lupus is one of skin problem.If you don't treat it timely.This skin problem may be lead to kidney problem .Do you want to know the relationship between lupus and Renal Disease ?The following content will tell you the answer for the questions.
Lupus is an autoimmune disease that can affect almost any part of your body,
most often your joints, skin, kidneys, heart, lungs, blood, or brain. Your two
kidneys are part of your renal system, which also includes two ureters, the
bladder, and the urethra. As the primary organs of the renal system, your
kidneys are responsible for:
Maintaining the correct amount and type of body fluids
Removing waste products and toxic substances
Regulating the hormones (chemical messengers) that help control blood
pressure and blood volume
Lupus Nephritis
Inflammation of the nephrons, the structures within the kidneys that filter
the blood, is called glomerulonephritis, or nephritis. Lupus nephritis is the
term used when lupus causes inflammation in your kidneys, making them unable to
properly remove waste from your blood or control the amount of fluids in your
body.
Abnormal levels of waste can build up in the blood, and edema (swelling) can
develop. Left untreated, nephritis can lead to scarring and permanent damage to
the kidneys and possibly end-stage renal disease (ESRD). People with ESRD need
regular filtering of their body’s waste done by a machine (dialysis) or a kidney
transplant so that at least one kidney is working properly.
Lupus nephritis most often develops within the first five years after the
symptoms of lupus start. It usually affects people between 20 and 40. In the
early stages of lupus nephritis, there are very few signs that anything is
wrong. Often the first symptoms of lupus nephritis are weight gain and puffiness
in your feet, ankles, legs, hands, and/or eyelids. This swelling often becomes
worse throughout the day. Also, your urine may be foamy or frothy, or have a red
color. The first signs of lupus nephritis often show up in clinical laboratory
tests on the urine.
It’s estimated that as many as 40 percent of all people with lupus, and as
many as two-thirds of all children with lupus, will develop kidney complications
that require medical evaluation and treatment. Testing your urine is very
important because there are so few symptoms of kidney disease. Significant
damage to your kidneys can happen before you are diagnosed with lupus.
Nephrologists are the physicians who treat the renal system. The tests they
will use to diagnose lupus nephritis are: Collection of urine, usually over a
24-hour period; blood tests; and often, a kidney biopsy.
Symptoms of Lupus Nephritis
Sudden and unexplained swelling, especially in the extremities (feet, ankles,
legs, fingers, arms) or the eyes
Blood in the urine
Elevated blood pressure
Foamy appearance in urine
Increased urination, especially at night
Urinalysis
Kidneys process your body’s waste matter. Therefore, testing a sample of your
urine can show any problems with the way your kidneys are functioning. The most
common tests look for cell casts (fragments of cells normally found in the
blood, or fragments of the tubules of the kidneys) and proteinuria (protein
being spilled into your body because your kidneys are not filtering the waste
properly).
Blood Tests
Certain blood tests can provide information about kidney damage and how well
your body is filtering waste. The creatinine blood test is usually ordered along
with a blood urea nitrogen (BUN) test to assess kidney function. A combination
of blood and urine creatinine levels may be used to calculate a creatinine
clearance. This measures how effectively your kidneys are filtering small
molecules like creatinine out of your blood. Serum creatinine measurements
(along with your age, weight, and gender) are used to calculate the estimated
glomerular filtration rate (EGFR), which is used as a screening test for
evidence of kidney damage.
Treatments
Micro-Chinese Medicine is a good choice for you to treat your kidney disease.This therapy based on Chinese Medicine and in other hand in virtual of a Western Machine.And in the whole treatment progress there are little pain than other treatment.